0        10        20        30
                                                      |         |         |         |
bostaur                   -----------------------------VPLGTTAKEEMERFWSKNTTLNRPLSPHISI
chicken                   MAALVLRCVARRCLLARLSPGPSVHHV--VPMATTAKEEMARFWEKNTKSSRPLSPHISI
Homo                      -----------------------------VPLGTTAKEEMERFWNKNIGSNRPLSPHITI
Drosoph                                              myalssslirspalrqglqmaaasrpvsmkvvsvaetqkdesf
                                                                     feknerlgrelsphlti
Rickettsiaprowazekii      ----------------------------------------MTKIKQEIYNKRPTSPHLTI
Chondruscrispus           ------------------------------------------MFIKFKISNRPIAPHLLV
Porphyrapurpurea          ----------------------------------------------MYNINRPISPHLTI
Marchantiapolymorpha      -----------------------------------------------MKINRPLSPHLTI
Reclinomonasamericana     -------------------------------MISINFNFLKIKGIINMNINRPISPHLTI
Paracoccusdenitrificans   -------------------------------------------MADVNRGNRPLSPHLQV
Caenorhabditisbriggsae    MINIPTSILCRLGARSAISRSFGTSVVTKSEAKTPIQKFGWEYLKKQRDMKRPIAPHLTI
EcoliSDH13991_DEECS4      -------------------------------------------MIRNVKKQRPVNLDLQT
                                                                             **   H:
Prim.cons.                                                               433NRP2SPHLTI

                                 40        50        60        70        80
                                  |         |         |         |         |
bostaur                   YGWSLPMAMSICHRGTGIALSAGVSLFGLSALLVPGSFESHLEFVKSLCLG---PALI
Homo                      YSWSLPMAMSICHRGTGIALSAGVSLFGMSALLLPGNFESYLELVKSLCLG---PALI
chicken                   YKWSLPMAMSITHRGTGVALSLGVSLFSLAALLLPEQFPHYVAVVKSLSLS---PALI
Drosoph                   yqpqltsmlsichrgtglalgvgvwglglgalisshdishyvtmveglqls---gatl
Rickettsiaprowazekii      YKPQISSTLSILHRMTGVALFFVVSILVWWLILSKYDNNYLQLASCC---------II
Chondruscrispus           YTPQLSSLFSIWHRISGVGLAFFFTTFLIFIRIILSSNFACNLLTLISFEI--SQWII
Porphyrapurpurea          YNTQKSSLFSIWHRISGVAMFTLIASPPLFLKLATFSYKSFNILDLMLNNS---SLIL
Marchantiapolymorpha      YKPQLTSTFSIFHRISGAFLATMVLFSILFFKIGDLSLTFYHFYQYFFFLTFYLNWFI
Reclinomonasamericana     YKLQITNTLSIFHRITGGVLALTLCFFILILKMLNFHLSSYAFYSIAYTLNQYSGFLF
Paracoccusdenitrificans   YRLPLAAITSIMTRITGHALVAGIVLITWWLVAAVTSPGAFACADWVVR-----SWLG
Caenorhabditisbriggsae    YQPQLTWMLSGFHRISGCVMAGTLLVGGLGFAVLPLDFTTFVEYIRGWNLP---CAVT
EcoliSDH13991_DEECS4      IRFPITAIASILHRVSGVITFVAVGILLWLLGTSLSSPEGFEQASAIMG-----SFFV
                          HHHHHH1HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--HHHHHHHHHH--HHHHH  .
Prim.cons.                YKPQLTST2SIFHRI2GVALAAGVSLFGLFLKLLPG3FS4F3224ASLCLGL44YSS2LI

                            90       100       110       120       130       140
                             |         |         |         |         |         |
bostaur                   HTAKFALVFPLMYHTWNGIRHLMWDLGKGLTISQLHQSGVAVLVLTVLSSVGLAAM---
Homo                      HTAKFALVFPLMYHTWNGIRHLMWDLGKGLKIPQLYQSGVVVLVLTVLSSMGLAAM---
chicken                   YSAKFALVFPLSYHTWNGIRHLVWDMGKGFKLSQVEQSGVVVLILTLLSSAGIAAIS--
Drosoph                   talkfiiaypagyhtangirhllwdtgrflkikevystgyamvatsfvlsailall---
Rickettsiaprowazekii      KICLVAFSYSWCYHLCNGIRHLFWDIGYGFSIKAVNITGWCVVVCSILLTMLLWV----
Chondruscrispus           IYFNLFILLFLFYHLFNGTRHIIWDFGFLLDIKYLSKFSLFLLVSLSLILIFQ------
Porphyrapurpurea          PWFIVIISVIFLYHIINGIRHFLWDSVVNVNTESIIKDSNTLLALVFLIMLFKFIL---
Marchantiapolymorpha      ISLVNFTLLALCYHMSNGVRHLLWDLGFFLELSKVYTSGIIMLFCAAFLALLNIIRQHWSNGQIPY
Reclinomonasamericana     IAISFFLLLFIFYHLFAGLRHLVWDAGYALEIENVYLTGYIMLGLAFLFTLIAWIIF--
Paracoccusdenitrificans   FIILTGSMWALWYHLLAGLRHLFYDAGYGLEIEQAHKSSQALIAGSVVLAVLTLIVFFVF
Caenorhabditisbriggsae    AVFKYIIAFPIIFHTLNGIRFLGFDLAKGVDNIGQVYKSGWLVFGVSAVIALAIVINSCQNKSKAVKTA
EcoliSDH13991_DEECS4      KFIMWGILTALAYHVVVGIRHMMMDFGYLEETFEAGKRSAKISFVITVVLSLLAGVLVW-
                          HHHHHHHHHHHHHHHHHHHHHHHHHH-------HHHHHHHHHHHHHHHHHHHHHHHHHH
Prim.cons.                I22KF2IL22L3YHL3NGIRHLMWDLGYGLE2IEQVYKSG2IVLVL2VLL2LLL2I2F43
 

        1 myalssslirspalrqglqm aaasrpvsmk vvsvaetqkd esffeknerl grelsphlti
       61 yqpqltsmls ichrgtglal gvgvwglglg alisshdish yvtmveglql sgatltalkf
      121 iiaypagyht angirhllwd tgrflkikev ystgyamvat sfvlsailal l